Giovanni Martinelli Selected Research

Interferon-alpha (Interferon Alfa)

8/2010	The response to imatinib and interferon-alpha is more rapid than the response to imatinib alone: a retrospective analysis of 495 Philadelphia-positive chronic myeloid leukemia patients in early chronic phase.
7/2009	Interferon-alpha may restore sensitivity to tyrosine-kinase inhibitors in Philadelphia chromosome positive acute lymphoblastic leukaemia with F317L mutation.
5/2008	Front-line treatment of Philadelphia positive chronic myeloid leukemia with imatinib and interferon-alpha: 5-year outcome.
1/2006	Comparison between patients with Philadelphia-positive chronic phase chronic myeloid leukemia who obtained a complete cytogenetic response within 1 year of imatinib therapy and those who achieved such a response after 12 months of treatment.
12/2004	Imatinib and pegylated human recombinant interferon-alpha2b in early chronic-phase chronic myeloid leukemia.
1/2003	Interferon-alfa for chronic myeloid leukemia.
7/2002	Novel types of bcr-abl transcript with breakpoints in BCR exon 8 found in Philadelphia positive patients with typical chronic myeloid leukemia retain the sequence encoding for the DBL- and CDC24 homology domains but not the pleckstrin homology one.
3/2002	A randomized study of interferon-alpha versus interferon-alpha and low-dose arabinosyl cytosine in chronic myeloid leukemia.

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Giovanni Martinelli Research Topics

Disease

101	Neoplasms (Cancer) 12/2023 - 07/2002
101	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2023 - 03/2002
74	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2024 - 05/2002
59	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2023 - 04/2004
36	Philadelphia Chromosome 01/2023 - 07/2002
35	Leukemia 01/2023 - 11/2006
32	Multiple Myeloma 04/2022 - 10/2002
24	Hematologic Neoplasms (Hematological Malignancy) 11/2022 - 06/2004
20	Lymphoma (Lymphomas) 01/2023 - 01/2003
19	Residual Neoplasm 05/2024 - 12/2006
15	Infections 01/2021 - 10/2003
13	Breast Neoplasms (Breast Cancer) 03/2023 - 09/2002
13	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2019 - 05/2007
11	Non-Hodgkin Lymphoma (Lymphosarcoma) 08/2020 - 06/2002
10	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2017 - 06/2004
9	Febrile Neutropenia 08/2022 - 10/2007
8	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2020 - 07/2007
7	Disease Progression 01/2022 - 07/2011
7	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2021 - 09/2008
7	Blast Crisis (Blast Phase) 08/2017 - 06/2005
6	Neoplasm Metastasis (Metastasis) 06/2023 - 09/2002
6	COVID-19 05/2021 - 01/2020
6	Thrombocytopenia (Thrombopenia) 10/2019 - 09/2004
6	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 06/2017 - 10/2003
5	Neutropenia 08/2022 - 09/2004
5	Acute Promyelocytic Leukemia 11/2019 - 04/2003
5	Pathologic Complete Response 09/2011 - 10/2005
5	Cardiotoxicity 05/2010 - 08/2005
4	Hypoxia (Hypoxemia) 01/2024 - 04/2014
4	Fever (Fevers) 01/2023 - 09/2005
4	Inflammation (Inflammations) 12/2022 - 09/2007
4	B-Cell Lymphoma (Lymphoma, B Cell) 07/2014 - 10/2003
4	Hypereosinophilic Syndrome (Loeffler Endocarditis) 04/2008 - 02/2004
3	Anemia 01/2024 - 04/2008
3	Lung Neoplasms (Lung Cancer) 06/2023 - 11/2008
3	Carcinogenesis 02/2023 - 09/2007
3	Fatigue 12/2022 - 01/2017
3	Hodgkin Disease (Hodgkin's Disease) 08/2022 - 01/2009

Drug/Important Bio-Agent (IBA)

78	Imatinib Mesylate (Gleevec)FDA Link 12/2023 - 03/2003
53	Tyrosine Kinase InhibitorsIBA 01/2023 - 03/2004
22	Phosphotransferases (Kinase)IBA 02/2023 - 06/2005
22	Proteins (Proteins, Gene)FDA Link 09/2022 - 06/2003
20	Rituximab (Mabthera)FDA Link 01/2022 - 10/2003
16	nilotinib FDA Link 01/2021 - 06/2007
14	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2021 - 06/2003
14	Dasatinib (BMS 354825)FDA Link 01/2021 - 11/2006
12	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2022 - 09/2002
10	Monoclonal AntibodiesIBA 03/2021 - 06/2002
9	Biomarkers (Surrogate Marker)IBA 01/2023 - 02/2009
9	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 12/2008
8	Chimeric Antigen ReceptorsIBA 03/2023 - 10/2019
8	bcr-abl Fusion ProteinsIBA 09/2013 - 06/2003
8	Interferon-alpha (Interferon Alfa)IBA 08/2010 - 03/2002
7	LigandsIBA 01/2024 - 12/2005
7	fms-Like Tyrosine Kinase 3IBA 01/2023 - 10/2019
7	blinatumomabIBA 01/2023 - 06/2017
7	AntigensIBA 10/2022 - 04/2016
7	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 08/2022 - 08/2003
7	ponatinibIBA 01/2022 - 10/2013
6	EnzymesIBA 06/2023 - 09/2007
6	Lenalidomide (CC 5013)FDA Link 01/2022 - 01/2020
6	Inotuzumab OzogamicinIBA 01/2022 - 08/2016
6	Gemtuzumab (Mylotarg)FDA Link 09/2021 - 09/2004
6	Azacitidine (5 Azacytidine)FDA Link 01/2021 - 08/2009
5	venetoclaxIBA 01/2024 - 01/2023
5	Immune Checkpoint InhibitorsIBA 01/2023 - 01/2019
5	RG7388IBA 01/2023 - 01/2016
5	Filgrastim (Neupogen)FDA Link 08/2022 - 01/2006
5	Everolimus FDA Link 06/2022 - 02/2010
5	SteroidsIBA 01/2022 - 05/2007
5	Messenger RNA (mRNA)IBA 10/2021 - 07/2002
5	quizartinibIBA 01/2021 - 01/2018
5	Protein Isoforms (Isoforms)IBA 01/2021 - 07/2005
5	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 09/2013
5	Chlorambucil (Leukeran)FDA Link 06/2017 - 10/2003
4	TOR Serine-Threonine KinasesIBA 02/2023 - 05/2007
4	gilteritinibIBA 01/2023 - 10/2019
4	glasdegibIBA 01/2023 - 08/2015
4	pegfilgrastim (Neulasta)FDA Link 08/2022 - 12/2010
4	Proteasome InhibitorsIBA 03/2021 - 01/2013
4	Bortezomib (Velcade)FDA Link 12/2020 - 03/2016
4	Etoposide (VP 16)FDA LinkGeneric 07/2020 - 10/2005
4	CateninsIBA 10/2017 - 09/2013
4	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 04/2008 - 01/2003
3	Alanine Transaminase (SGPT)IBA 01/2023 - 01/2017
3	AnthracyclinesIBA 01/2023 - 01/2006
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2023 - 08/2020
3	NucleotidesIBA 08/2022 - 11/2016
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 08/2022 - 01/2020
3	Sirolimus (Rapamycin)FDA Link 06/2022 - 12/2012

Therapy/Procedure

113	Therapeutics 01/2024 - 07/2002
60	Drug Therapy (Chemotherapy) 01/2024 - 09/2002
23	Stem Cell Transplantation 01/2021 - 09/2003
9	Immunotherapy 05/2024 - 04/2016
6	Radiotherapy 06/2023 - 06/2009
6	Transplantation 01/2023 - 11/2011
6	Autologous Transplantation 12/2020 - 09/2003
4	Hematopoietic Stem Cell Transplantation 01/2021 - 05/2013
4	Salvage Therapy 01/2019 - 09/2007
3	Precision Medicine 10/2023 - 09/2021